Organizational approaches to managing information systems (IS) professionals have been making headlines as technology-intensive businesses search for ways to cope with an ever-changing economic landscape. Consequently, understanding and predicting employee quitting or separation behavior is crucial. We incorporate human capital theory from economics to form an alternative theoretical perspective for understanding IS professionals' separation and retention. This shift allows us to focus on precursors to observed separation, rather than attitudinal precursors of intentions. We introduce three new constructs: pressure to separate, retention frontiers, and separation thresholds. These constructs provide a basis for identifying when an employee is close to leaving the firm and for a new approach to analyze the potential effectiveness of action taken by a firm to change separation behavior: pre-implementation retention intervention assessment (PRI-assessment). We illustrate the application of the new approach using data on the observed separation behavior of 661 IS professionals at a large multidivision firm.